RStudio: menu items, commands, no response after installation.

As a last resort, you can also try uninstalling and reinstalling both R and RStudio.

If that still doesn't work, the only other guess I have is that this could be related to some other software installed and running on the machine that is somehow interfering with RStudio's normal processing. Some examples we've seen before:

It could be worth investigating whether closing some of the other software on your machine makes a difference.