New Mac, R studio loaded, deseq2 not working

I have been working on R studio, using a PC, in a server environment where we had every good support. I am now in a new place, where I have been given a macpro, and I have to load and start up R studio in desktop. I am struggling a bit and need help to get started please.

So I downloaded R, R studio. version info as below.
platform x86_64-apple-darwin17.0
arch x86_64
os darwin17.0
system x86_64, darwin17.0
major 4
minor 0.3
year 2020
month 10
day 10
svn rev 79318
language R
version.string R version 4.0.3 (2020-10-10)
nickname Bunny-Wunnies Freak Out

I then wanted to load DeSeq2. Seeing R is version 4, I ran

if (!requireNamespace("BiocManager", quietly = TRUE))

I am getting the following error:

The downloaded binary packages are in

What does this mean ? And how do I get started please? Thanks


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