X2Go and RStudio

first I test by uncomment in /etc/x2go/x2goagent.options, perhaps it's not the best solution, but studio start .

Uncomment to disable GLX, the old mesa version is hopelessly outdated anyways.
Unbreaks the gnome3 control center

X2GO_NXAGENT_DEFAULT_OPTIONS+=" -extension GLX"

Then GLX 1.4 is ok for me,it 's not exactly the same problem, if you look version of my softwares

$ glxinfo | grep 'GLX version:'
GLX version: 1.4

and glxdemo, glxgears, glxheads, glxinfo work properly

Debian Buster

x2goserver: 4.1.0.3
x2goserver-common: 4.1.0.3
x2goserver-extensions: 4.1.0.3
x2goserver-fmbindings: 4.1.0.3
x2goserver-printing: 4.1.0.3
x2goserver-x2goagent: 3.5.99.20
x2goserver-xsession: 4.1.0.3
GLX version: 1.4